GNAL Mouse Monoclonal Antibody [Clone ID: OTI2F3]

Specifications

Product Data
Clone Name	OTI2F3
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-120 of human GNAL (NP_892023) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	52.3 kDa
Gene Name	G protein subunit alpha L
Database Link	NP_892023 Entrez Gene 14680 MouseEntrez Gene 24611 RatEntrez Gene 2774 Human UniProt ID P38405
Background	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters. [UniProtKB/Swiss-Prot Function]
Synonyms	DYT25
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Calcium signaling pathway, Olfactory transduction

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