ARTS1 (ERAP1) Mouse Monoclonal Antibody [Clone ID: OTI7G4]

Specifications

Product Data
Clone Name	OTI7G4
Applications	WB
Recommend Dilution	WB 1:250~500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 529-941 of human ERAP1 (NP_001035548) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	107.1 kDa
Gene Name	endoplasmic reticulum aminopeptidase 1
Database Link	NP_001035548 Entrez Gene 80897 RatEntrez Gene 80898 MouseEntrez Gene 51752 Human UniProt ID Q9NZ08
Background	The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Synonyms	A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP
Reference Data
Protein Families	Druggable Genome, Protease, Secreted Protein

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