GTF3C4 Mouse Monoclonal Antibody [Clone ID: OTI4A3]

Specifications

Product Data
Clone Name	OTI4A3
Applications	IHC, WB
Recommend Dilution	WB 1:500, IHC 1:750
Reactivity	Human, Monkey, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 583-822 of human GTF3C4 (NP_036336) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	general transcription factor IIIC subunit 4
Database Link	NP_036336 Entrez Gene 714849 MonkeyEntrez Gene 9329 Human UniProt ID Q9UKN8
Background	Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. [UniProtKB/Swiss-Prot Function]
Synonyms	KAT12; TF3C-delta; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA
Reference Data
Protein Families	Transcription Factors

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