ROR2 Mouse Monoclonal Antibody [Clone ID: OTI3F8]

Specifications

Product Data
Clone Name	OTI3F8
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:250
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 796-927 of human ROR2(NP_004551) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	101.3 kDa
Gene Name	receptor tyrosine kinase like orphan receptor 2
Database Link	NP_004551 Entrez Gene 26564 MouseEntrez Gene 306782 RatEntrez Gene 4920 Human UniProt ID Q01974
Background	The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq, Jul 2008]
Synonyms	BDB; BDB1; NTRKR2
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transmembrane

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