GRB7 Mouse Monoclonal Antibody [Clone ID: OTI15E7]

Specifications

Product Data
Clone Name	OTI15E7
Applications	WB
Recommend Dilution	WB 1:500~2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human GRB7 (NP_005301) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	59.5 kDa
Gene Name	growth factor receptor bound protein 7
Database Link	NP_005301 Entrez Gene 14786 MouseEntrez Gene 84427 RatEntrez Gene 2886 Human UniProt ID Q14451
Background	The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Synonyms	growth factor receptor-bound protein 7; OTTHUMP00000164352
Reference Data
Protein Families	Druggable Genome, Embryonic stem cells, Stem cell - Pluripotency

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