MAVS Mouse Monoclonal Antibody [Clone ID: OTI8A11]

Specifications

Product Data
Clone Name	OTI8A11
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-247 of human MAVS(NP_065797) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	56.3 kDa
Gene Name	mitochondrial antiviral signaling protein
Database Link	NP_065797 Entrez Gene 57506 Human UniProt ID Q7Z434
Background	This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Synonyms	CARDIF; IPS-1; IPS1; VISA
Reference Data
Protein Families	Transmembrane
Protein Pathways	Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

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