CGK2 (PRKG2) Mouse Monoclonal Antibody [Clone ID: OTI10D5]

Specifications

Product Data
Clone Name	OTI10D5
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 40-320 of human PRKG2(NP_006250 produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	87.3 kDa
Gene Name	protein kinase cGMP-dependent 2
Database Link	NP_006250 Entrez Gene 19092 MouseEntrez Gene 25523 RatEntrez Gene 5593 Human UniProt ID Q13237
Background	This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Synonyms	cGK2; cGKII; PRKGR2
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Gap junction, Long-term depression, Olfactory transduction

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