hSET1 (SETD1A) Mouse Monoclonal Antibody [Clone ID: OTI7B7]

Specifications

Product Data
Clone Name	OTI7B7
Applications	IHC, WB
Recommend Dilution	WB 1:500, IHC 1:150
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-320 of human SETD1A(NP_055527) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	185.9 kDa
Gene Name	SET domain containing 1A, histone lysine methyltransferase
Database Link	NP_055527 Entrez Gene 233904 MouseEntrez Gene 9739 Human UniProt ID O15047
Background	SET1A is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. The complex is the analog of the S. cerevisiae Set1/COMPASS complex (Lee and Skalnik, 2005 [PubMed 16253997]). Also see SET1B (MIM 611055). [supplied by OMIM, Mar 2008]
Synonyms	KMT2F; Set1; Set1A
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Lysine degradation

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