L Kynurenine Hydrolase (KYNU) Mouse Monoclonal Antibody [Clone ID: OTI1H1]

Specifications

Product Data
Clone Name	OTI1H1
Applications	IHC
Recommend Dilution	IHC 1:150
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-216 of human KYNU (NP_001028170) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	34.5 kDa
Gene Name	kynureninase
Database Link	NP_001028170 Entrez Gene 116682 RatEntrez Gene 8942 Human UniProt ID Q16719
Background	Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Synonyms	KYNUU
Reference Data
Protein Families	Protease
Protein Pathways	Metabolic pathways, Tryptophan metabolism

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