PIK3R5 Mouse Monoclonal Antibody [Clone ID: OTI2C6]
CAT#: CF505893
Carrier-free (BSA/glycerol-free) PIK3R5 mouse monoclonal antibody, clone OTI2C6 (formerly 2C6)
Formulation: Standard
View other "OTI2C6" antibodies (4)
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI2C6 |
Applications | IF, IHC, WB |
Recommend Dilution | WB 1:200~2000, IHC 1:150, IF 1:100 |
Reactivity | Human, Dog, Rat, Monkey, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PIK3R5(NP_055123) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 97.2 kDa |
Gene Name | phosphoinositide-3-kinase regulatory subunit 5 |
Database Link | |
Background | Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011] |
Synonyms | F730038I15Rik; FOAP-2; p101; P101-PI3K |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Acute myeloid leukemia, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Glioma, Insulin signaling pathway, Jak-STAT signaling pathway, Leukocyte transendothelial migration, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA505893 | PIK3R5 mouse monoclonal antibody, clone OTI2C6 (formerly 2C6) |
CNY 1,999.00 |
|
TA505893AM | PIK3R5 mouse monoclonal antibody,clone 2C6, Biotinylated |
CNY 3,990.00 |
|
TA505893BM | PIK3R5 mouse monoclonal antibody,clone 2C6, HRP conjugated |
CNY 3,990.00 |
|
TA505893S | PIK3R5 mouse monoclonal antibody, clone OTI2C6 (formerly 2C6) |
CNY 800.00 |