Lipoprotein lipase (LPL) Mouse Monoclonal Antibody [Clone ID: OTI3A10]

Specifications

Product Data
Clone Name	OTI3A10
Applications	FC, IHC, WB
Recommend Dilution	WB 1:500, IHC 1:150, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 28-475 of human LPL(NP_000228) produced in HEK293T.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50.3 kDa
Gene Name	lipoprotein lipase
Database Link	NP_000228 Entrez Gene 16956 MouseEntrez Gene 24539 RatEntrez Gene 4023 Human UniProt ID P06858
Background	LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq]
Synonyms	HDLCQ11; LIPD
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Alzheimer's disease, Glycerolipid metabolism, PPAR signaling pathway

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