APBB3 Mouse Monoclonal Antibody [Clone ID: OTI5G3]

Specifications

Product Data
Clone Name	OTI5G3
Applications	FC, IHC, WB
Recommend Dilution	WB 1:500, IHC 1:150, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinan protein of human APBB3(NP_573419) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	52.4 kDa
Gene Name	amyloid beta precursor protein binding family B member 3
Database Link	NP_573419 Entrez Gene 117026 RatEntrez Gene 225372 MouseEntrez Gene 10307 Human UniProt ID O95704
Background	The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]
Synonyms	FE65L2; SRA
Reference Data

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