XPNPEP3 Mouse Monoclonal Antibody [Clone ID: OTI4B8]

Specifications

Product Data
Clone Name	OTI4B8
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Dog, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human XPNPEP3(NP_071381) produced in HEK293 cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	56.9 kDa
Gene Name	X-prolyl aminopeptidase 3
Database Link	NP_071381 Entrez Gene 321003 MouseEntrez Gene 685823 RatEntrez Gene 481237 DogEntrez Gene 705778 MonkeyEntrez Gene 63929 Human UniProt ID Q9NQH7
Background	The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.
Synonyms	APP3; ICP55; NPHPL1
Reference Data
Protein Families	Druggable Genome, Protease

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