NORE1 (RASSF5) Mouse Monoclonal Antibody [Clone ID: OTI1C6]

Specifications

Product Data
Clone Name	OTI1C6
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human RASSF5 (NP_872606) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	30.2 kDa
Gene Name	Ras association domain family member 5
Database Link	NP_872606 Entrez Gene 54354 MouseEntrez Gene 54355 RatEntrez Gene 83593 Human UniProt ID Q8WWW0
Background	This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms	Maxp1; NORE1; NORE1A; NORE1B; RAPL; RASSF3
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Leukocyte transendothelial migration, Non-small cell lung cancer, Pathways in cancer

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