Aquaporin 1 (AQP1) Mouse Monoclonal Antibody [Clone ID: OTI10C11]

Specifications

Product Data
Clone Name	OTI10C11
Applications	FC, WB
Recommend Dilution	WB 1:2000, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human AQP1 (NP_932766) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	28.3 kDa
Gene Name	aquaporin 1 (Colton blood group)
Database Link	NP_932766 Entrez Gene 11826 MouseEntrez Gene 25240 RatEntrez Gene 358 Human UniProt ID P29972
Background	Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms	AQP-CHIP; CHIP28; CO
Reference Data
Protein Families	Druggable Genome, Ion Channels: Other, Transmembrane

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