SPR Mouse Monoclonal Antibody [Clone ID: OTI2C6]

Specifications

Product Data
Clone Name	OTI2C6
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150, FLOW 1:100, IF: 1:100
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SPR(NP_003115) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	27.9 kDa
Gene Name	sepiapterin reductase
Database Link	NP_003115 Entrez Gene 705317 MonkeyEntrez Gene 6697 Human UniProt ID P35270
Background	This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq]
Synonyms	SDR38C1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Folate biosynthesis, Metabolic pathways

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