MTMR14 Mouse Monoclonal Antibody [Clone ID: OTI6B6]

Specifications

Product Data
Clone Name	OTI6B6
Applications	FC, IF, WB
Recommend Dilution	WB 1:500~2000, IF 1:100, FLOW 1:100
Reactivity	Human, Dog, Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MTMR14 (NP_001070993) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	72.0 kDa
Gene Name	myotubularin related protein 14
Database Link	NP_001070993 Entrez Gene 97287 MouseEntrez Gene 312634 RatEntrez Gene 484668 DogEntrez Gene 64419 Human UniProt ID Q8NCE2
Background	This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.
Synonyms	C3orf29
Reference Data
Protein Families	Druggable Genome, Phosphatase, Secreted Protein

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