NEK11 Mouse Monoclonal Antibody [Clone ID: OTI5D9]

Specifications

Product Data
Clone Name	OTI5D9
Applications	IF, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, IF 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human NEK11(NP_079076) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	74 kDa
Gene Name	NIMA related kinase 11
Database Link	NP_079076 Entrez Gene 79858 Human UniProt ID Q8NG66
Background	This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.
Synonyms	FLJ23495
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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