GNMT Mouse Monoclonal Antibody [Clone ID: OTI8A3]

Specifications

Product Data
Clone Name	OTI8A3
Applications	FC, WB
Recommend Dilution	WB: 1:200 - 1:1000, Flow 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human GNMT (NP_061833) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	32.6 kDa
Gene Name	glycine N-methyltransferase
Database Link	NP_061833 Entrez Gene 27232 Human UniProt ID Q14749
Background	The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).
Synonyms	glycine N-methyltransferase; OTTHUMP00000016412
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Glycine, serine and threonine metabolism

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