Natriuretic Peptide Receptor C (NPR3) Mouse Monoclonal Antibody [Clone ID: OTI2B12]

Specifications

Product Data
Clone Name	OTI2B12
Applications	FC, IF, WB
Recommend Dilution	WB 1:1000, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human NPR3 (NP_000899) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	59.8 kDa
Gene Name	natriuretic peptide receptor 3
Database Link	NP_000899 Entrez Gene 18162 MouseEntrez Gene 25339 RatEntrez Gene 4883 Human UniProt ID P17342
Background	The family of natriuretic peptides (see MIM 108780) elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain
Synonyms	ANP-C; ANPR-C; ANPRC; C5orf23; GUCY2B; NPR-C; NPRC
Reference Data
Protein Families	Druggable Genome, Transmembrane

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