STK3 Mouse Monoclonal Antibody [Clone ID: OTI4G10]

Specifications

Product Data
Clone Name	OTI4G10
Applications	IHC, WB
Recommend Dilution	WB 1:2000; IHC 1:50
Reactivity	Human, Monkey, Dog, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full-length protein expressed in 293T cell transfected with human STK3 expression vector
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	56.3 kDa
Gene Name	serine/threonine kinase 3
Database Link	NP_006272 Entrez Gene 56274 MouseEntrez Gene 65189 RatEntrez Gene 475045 DogEntrez Gene 707425 MonkeyEntrez Gene 6788 Human UniProt ID Q13188
Background	Protein kinase activation is a frequent response of cells to treatment with growth factors,chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast ' sterile 20'(Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand
Synonyms	KRS1; MST2
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	MAPK signaling pathway

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.