Cardiac Troponin I (TNNI3) Mouse Monoclonal Antibody [Clone ID: OTI3G2]

CAT#: CF500255

Carrier-free (BSA/glycerol-free) TNNI3 mouse monoclonal antibody, clone OTI3G2 (formerly 3G2)

Formulation: Standard Carrier-Free



  View other "OTI3G2" antibodies (4)

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CNY 3,999.00


货期*
2周

规格
    • 100 ug

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Specifications

Product Data
Clone Name OTI3G2
Applications IHC, WB
Recommend Dilution WB 1:2000 IHC 1:50
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Recombinant protein expressed in E.coli corresponding to amino acids 1-210 of human TNNI3
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 32.7 kDa
Gene Name troponin I3, cardiac type
Background Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM)
Synonyms CMD1FF; CMD2A; CMH7; cTnI; RCM1; TNNC1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency
Protein Pathways Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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