KRT81 Guinea Pig Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Immunoblotting: 1/2,000 for Western blotting (ECL method). Immunofluorescence Microscopy on Frozen Sections. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/200 for 1h at RT (Trypsin and Microwave pretreatment is required).
Reactivity	Human, Mouse
Host	Guinea Pig
Clonality	Polyclonal
Immunogen	Synthetic peptide of Human basic hair (trichocytic) keratin K81 (formerly also designated keratin hHb1) coupled to KLH
Specificity	The antiserum stains specifically Human hair Keratin K81 present in the hair cortex and hair cuticle and tumors derived therefrom.
Formulation	State: Serum State: Liquid Stabilized Antiserum Preservative: 0.09% Sodium Azide, 0.5% BSA
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	keratin 81
Database Link	Entrez Gene 3887 Human UniProt ID Q14533
Background	KRT81 (Keratin 81) is a type II hair keratin. It is a basic protein which heterodimerizes with type I keratins to form hair and nails. It is found primarily in the hair cortex. Mutations in KRT81 have been observed in patients with, monilethrix, a rare dominant hair disease characterized by beaded or moniliform hair that results from the periodic thinning of the hair shaft and shows a high propensity to excess weathering and fracturing.
Synonyms	KRT81, KRTHB1, MLN137, Keratin hair basic 1, ghHKb1, ghHb1, Keratin-81, K81, K2.9, MLN 137
Reference Data

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