pan Cytokeratin Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin-Embedded Tissue (Proteolytic treatment with Trypsin is recommended). Working Dilution: 1/50 (optimize by serial dilution). Dilution Buffer: Dilute immediately before use with PBS or TBS. Incubation time: 1 h at room temperature. Recommended Positive Control: Squamous cell carcinoma, skin, cervix.
Reactivity	Human, Mammalian
Host	Rabbit
Clonality	Polyclonal
Immunogen	Human skin.
Specificity	This antibody reacts positively with all stratified squamous epithelia and epidermal appendages such as hairfollicles, sebaceous glands. Also positive on epithelia of the urinary tract, stomach, intestine, uterine endometrium and prostate. Identifies mesotheliomas, squamous cell carcinomas, adenocarcinomas, transitional cell carcinomas and anaplastic carcinomas.
Formulation	PBS or TBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
Synonyms	pan Keratin, Cytokeratin pan-reactive
Reference Data

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