GLP1 (GCG) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry of Frozen and Paraffin Embedded Sections (No proteolytic treatment required). Working Dilution: 1/50-1/100, dilute immediately before use with PBS (0.15M Phosphate Buffered Saline). Incubation Time: 1 h at room temperature or overnight at 2-8°C. Positive Control: Pancreas.
Reactivity	Human, Mouse, Porcine, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Porcine pancreatic Glucagon/BSA
Specificity	The antibody is specific to pancreatic Glucagon. Antigen Localization: Cytoplasmic.
Formulation	State: Serum State: Liquid Serum
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	glucagon
Database Link	Entrez Gene 2641 Human UniProt ID P01275
Background	Glucagon is produced by the alpha-cells of the pancreatic islets. It occurs also in endocrine cells of the gut and in neurons in the brain. Glucagon is a common constituent of endocrine pancreatic tumours and of rectal carcinoids, such tumours may give rise to the so called glucagonoma syndrome. The antigen localization is cytoplasmic. VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagons hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth.
Synonyms	GCG
Reference Data

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