Gastrin (GAST) Guinea Pig Polyclonal Antibody

CAT#: BP5046

Gastrin (GAST) guinea pig polyclonal antibody, Serum



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CNY 5,291.00


货期*
5周

规格
    • 50 ul

Cited in 6 publications.

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Specifications

Product Data
Applications IF, IHC
Recommend Dilution Immunohistochemistry on Frozen Sections: 1:1,000-1:1,500
Immunohistochemistry on Paraffin Embedded Tissues: 1:1,000-1:1,500 (microwave treatment recommended)
Immunofluorescence Microscopy.
Recommended Positive Control: Formalin-fixed paraffin sections of Rat antrum.
Working Dilutions: 1:1,000-1:1,500 using FITC, with overnight incubation at 2-8°C.
Reactivity Human, Rat
Host Guinea Pig
Clonality Polyclonal
Immunogen Synthetic Human Gastrin I conjugated to BSA
Specificity Gastrin-secreting cells are numerous in the antrum and a few are found in the proximal duodenum. The antibody can be used for the diagnosis of Gastrin-producing tumors which are mainly found in the pancreas and occasionally in the stomach and the duodenum.
Absorption with 10-100 µg Gastrin 1-34 and CCK 8 per ml antiserum abolishes the staining.
Formulation State: Serum
State: Lyophilized Serum
Reconstitution Method Restore in 100 µl distilled water
Conjugation Unconjugated
Storage Condition

Prior to reconstitution store at 2-8°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Gene Name gastrin
Background Gastrin is mainly known by its first described role as a gastric acid-hormone but the protein also has the ability to promote cellular growth. More recently, gastrin has been suggested to induce leukocyte-endothelial cell interactions and to have a pro-inflammatory effect. Gastrin has two biologically active peptide forms, G34 and G17 and they activate two different receptors: the CCK-1 receptor, which has low affinity for gastrin but high affinity for the related hormone cholecystokinin (CCK), and the CCK-2 receptor, which has high affinity for both gastrin and CCK and mediates the acid-secretory as well as the proliferative effects of gastrin.
Synonyms GAST, GAS
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (6)

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