ITM2B Chicken Polyclonal Antibody

CAT#: BP4008

ITM2B chicken polyclonal antibody, Aff - Purified



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CNY 9,994.00


货期*
5周

规格
    • 200 ug

Product images

Specifications

Product Data
Applications IHC
Recommend Dilution Suitable for Immunohistochemistry on frozen sections.
Suggested positive control: pathological brain sections.
(Not recommended in Western blots).
Reactivity Human
Host Chicken
Clonality Polyclonal
Immunogen Peptide coupled to carrier protein.
Specificity The antibody recognizes the typical amyloid deposits in brains of patients suffering from the disease.
This antibody has been developed against the carboxy terminal extracellular sequence of the mutated BRI protein.
Formulation PBS, pH 7.2, containing 0.09% sodium azide as preservative.
State: Aff - Purified
State: Liquid purified Ig fraction.
Concentration 1.0 mg /ml
Purification Affinity chromatography.
Conjugation Unconjugated
Storage Condition Store the antibody at 2-8°C for one month or (in aliquots) at -20°C for longer.
Do not freeze working dilutions
Avoid repeated freezing and thawing.
Gene Name integral membrane protein 2B
Background The mutated BRI protein (ITM2B) was identified in patients with familial British dementia. The unusual 277 residue precursor protein releases a 34-residue amyloidogenic peptide by the action of the protease furin, leading to the deposition of a protein fragment that seems to be involved in the pathogenesis of familial British dementia.
Synonyms ITM2B, BRI, BRI2, Integral membrane protein 2B, Transmembrane protein BRI
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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