beta 2 Microglobulin (B2M) Mouse Monoclonal Antibody [Clone ID: B2M-01]

Specifications

Product Data
Clone Name	B2M-01
Applications	FC, WB
Recommend Dilution	Flow Cytometry: 1 μg/ml. Positive Control: Peripheral blood lymphocytes. Negative Control: DAUDI human Burkitt lymphoma cell line, erythrocytes.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified human beta2-microglobulin
Specificity	This antibody reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.
Formulation	Phosphate buffered saline (PBS) solution containing 15mM sodium azide Label: PE State: Liquid purified Ig fraction Label: Conjugated with R-Phycoerythrin under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Concentration	lot specific
Purification	Size-Exclusion Chromatography
Conjugation	PE
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	beta-2-microglobulin
Database Link	Entrez Gene 567 Human UniProt ID P61769
Background	Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.
Synonyms	B2M, Beta-2 microglobulin, Beta 2 microglobulin
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Antigen processing and presentation

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