Laminin alpha 5 (LAMA5) Mouse Monoclonal Antibody [Clone ID: 2D8/33 (4C7)]

Specifications

Product Data
Clone Name	2D8/33 (4C7)
Applications	ELISA, IF, IP
Recommend Dilution	ELISA. Immunoprecipitation. Immunofluorescence.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Human Laminin
Specificity	Reacts with the globular domain of the alpha-5 chain of intact Laminin and blocks the neurite stimulating activity of Laminin. It does not react with Rat and Mouse.
Formulation	State: Ascites State: Liquid Ascites containing 0.09% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	laminin subunit alpha 5
Database Link	Entrez Gene 3911 Human UniProt ID O15230
Background	Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. laminin 5 is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms	LAMA5, KIAA0533, KIAA1907, Laminin subunit alpha-5
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.