IGF1 Mouse Monoclonal Antibody [Clone ID: M23/ILG1-001]

Specifications

Product Data
Clone Name	M23/ILG1-001
Applications	ELISA, R
Recommend Dilution	ELISA (1/10,000-1/100,000). Radioimmunoassays.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Biosynthetic IGF-1.
Specificity	This antibody clone M23/ILG1-001 is specific for IGF-I. It shows minimal cross-reactivity with IGF-II, Proinsulin, MSF and Insulin.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	insulin like growth factor 1
Database Link	Entrez Gene 3479 Human UniProt ID P05019
Background	Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.
Synonyms	IGF-I, Somatomedin-C, Mechano growth factor, MGF, IBP1
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways	Dilated cardiomyopathy, Focal adhesion, Glioma, Hypertrophic cardiomyopathy (HCM), Long-term depression, Melanoma, mTOR signaling pathway, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer

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