Hepatitis B Surface Antigen / HBsAg (adw/ayw) Mouse Monoclonal Antibody [Clone ID: S35]

Specifications

Product Data
Clone Name	S35
Applications	ELISA, EM, IF, IHC
Recommend Dilution	ELISA Immunofluorescent. Immunoperoxidase staining. Immunoelectron Microscopy.
Reactivity	Hepatitis B Virus
Host	Mouse
Clonality	Monoclonal
Immunogen	HBsAg purified from Human sera pool. Source: Ascites.
Specificity	Recognizes HBsAg antigen (Adw/ayw).
Formulation	PBS, pH 7.2 without preservatives. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein A Sepharose Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing.
Background	Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
Synonyms	HBV surface antigen, Hepatitis B Virus
Reference Data

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