Hepatitis B Surface Antigen / HBsAg (ad/ay) Mouse Monoclonal Antibody [Clone ID: 86C]

Specifications

Product Data
Clone Name	86C
Applications	ELISA
Recommend Dilution	ELISA: As Detection antibody, use BM3315 for Capture and rapid assay formats.
Reactivity	Hepatitis B Virus
Host	Mouse
Clonality	Monoclonal
Immunogen	Native HBsAg (ad/ay)
Specificity	Recognizes Hepatitis B Surface Antigen (HBsAg), ad/ay subtype. Immunoreactive with all HBsAg A antigens.
Formulation	PBS without preservatives State: Purified State: Lyophilized purified Ig fraction
Reconstitution Method	Restore with Deionized water
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Background	Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
Synonyms	HBV surface antigen, Hepatitis B Virus
Reference Data

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