KEL Mouse Monoclonal Antibody [Clone ID: BRIC203]

Specifications

Product Data
Clone Name	BRIC203
Applications	AGG, ELISA, IHC
Recommend Dilution	Immunoprecipitation. Haemagglutination.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human Erythrocytes. Spleen cells from immunised Balb/c were fused with cells of a myeloma cell line.
Specificity	This antibody recognises CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on a 93kD erythrocyte membrane glycoprotein. In haemaggulation tests, BRIC203 reacts with Kp (a-b+) but not Kp (a+b-). In addition this antibody will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but not react with Ko Erythrocytes.
Formulation	Tris Buffered Glycine, pH 7.8 containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	Kell blood group, metallo-endopeptidase
Database Link	Entrez Gene 3792 Human UniProt ID P23276
Background	Blood Group Kell Antigen is a type II transmembrane glycoprotein. The Kell glycoprotein links to the XK membrane protein, that carries the Kx antigen via a single disulfide bond. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.
Synonyms	Kell blood group glycoprotein
Reference Data

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