PDGF Receptor beta (PDGFRB) Mouse Monoclonal Antibody [Clone ID: 21/72]

Specifications

Product Data
Clone Name	21/72
Applications	IF, IHC, IP, WB
Recommend Dilution	Flow Cytometry: 25 µg/ml. Immunoprecipitation. Western Blot. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections: 25 µg/ml. Recommended Positive Control: Human breast cancer tissue.
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Human skin fibroblast cell membrane extracts.
Specificity	This antibody is specific for the extracellular domain of the PDGF receptor beta subunit. This was confirmed in binding studies using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB. This antibody does not recognize PDGF receptor alpha. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.
Formulation	PBS, pH 7.2 containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	platelet derived growth factor receptor beta
Database Link	Entrez Gene 5159 Human UniProt ID P09619
Background	PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3.
Synonyms	PDGF-R-beta, PDGF Receptor beta
Reference Data

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