FAK (PTK2) pSer843 Rabbit Polyclonal Antibody
CAT#: AP55876PU-S
FAK (PTK2) pSer843 rabbit polyclonal antibody, Aff - Purified
Size: 100 ul
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CNY 1,400.00
货期*
2周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | Western blot: 1:500~1:1000. |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide sequence around phosphorylation site of serine843(R-G-S(p)-I-D) derived from Human FAK (KLH-conjugated) |
Specificity | The antibody detects endogenous level of FAK only when phosphorylated at serine 843. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography using epitope-specific peptide |
Conjugation | Unconjugated |
Storage Condition | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Predicted Protein Size | 120 kDa |
Gene Name | protein tyrosine kinase 2 |
Database Link | |
Background | Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. |
Synonyms | FAK, Focal adhesion kinase 1, FADK1, pp125FAK, Protein-tyrosine kinase 2 |
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