KCNQ4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Immunohistochemistry: 1/100 - 1/1000. Western Blot: 1/500 to 1/5000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from Nter domain of KCNQ4 protein
Specificity	This antibody reacts with 77 kDa KCNQ4 protein.
Formulation	0.1M Tris, 0.1M Glycine, 2% Sucrose State: Purified State: Lyophilized purified powder
Reconstitution Method	Restore in distilled water.
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	potassium voltage-gated channel subfamily Q member 4
Database Link	Entrez Gene 9132 Human UniProt ID P56696
Background	Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinnic receptors.
Synonyms	KCNQ4, Voltage-gated potassium channel subunit Kv7.4, Potassium channel subunit alpha KvLQT4, KQT-like 4
Reference Data

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