UGT8 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1:1;000. Western blot: 1:100~500. Immunohistochemistry on paraffin sections: 1:10~50.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 373-401 amino acids from the Central region of human UGT8
Specificity	This antibody detects UGT8 / UGT4 (Center).
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	UDP glycosyltransferase 8
Database Link	Entrez Gene 7368 Human UniProt ID Q16880
Background	Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides consists of the transfer of galactose to ceramide catalyzed by UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45). The enzyme encoded by the CGT gene is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte. [supplied by OMIM].
Synonyms	UDP-galactose-ceramide galactosyltransferase, Ceramide UDP-galactosyltransferase, Cerebroside synthase, CGT
Note	Molecular Weight: 61438 Da
Reference Data
Protein Families	Transmembrane
Protein Pathways	Metabolic pathways, Sphingolipid metabolism

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