UBE2D2 (C-term) Rabbit Polyclonal Antibody
CAT#: AP54437PU-N
UBE2D2 (C-term) rabbit polyclonal antibody, Aff - Purified
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CN¥ 6,160.00
货期*
2周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | ELISA: 1:1;000. Western blot: 1:100~500. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D2 |
Specificity | This antibody detects UBE2D2 (C-term). |
Formulation | PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein A column followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Gene Name | ubiquitin conjugating enzyme E2 D2 |
Database Link | |
Background | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. |
Synonyms | Ubiquitin-conjugating enzyme E2 D2, Ubiquitin-protein ligase D2, Ubiquitin carrier protein D2, UBC4, UBCH5B, E2(17)KB 2 |
Note | Molecular Weight: 16735 Da |
Reference Data | |
Protein Pathways | Ubiquitin mediated proteolysis |
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