TRPC1 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:1;000. Western blot: 1:100~500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 764-793 amino acids from the C-terminal region of human TRPC1
Specificity	This antibody detects TRPC1 / TRP1 (C-term).
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	transient receptor potential cation channel subfamily C member 1
Database Link	Entrez Gene 7220 Human UniProt ID P48995
Background	TRPC1 belongs to the transient receptor potential (TRP) superfamily of cation channels. TRP cation channels are involved in diverse physiologic processes, including receptor- and store-operated Ca(2+) entry, mineral absorption, and cell death. They also function as sensors for pain, heat, cold, sound, stretch, and osmotic changes (Zhang et al., 2009 [PubMed 19193631]).
Synonyms	Transient receptor protein 1, TRP-1
Note	Molecular Weight: 91212 Da
Reference Data
Protein Families	Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
Protein Pathways	Calcium signaling pathway, Huntington's disease, Parkinson's disease

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