Phospholipase C beta 1 (PLCB1) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500. Flow Cytometry: 1/10-1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 1155~1184 amino acids from the C-terminal region of human PLCB1
Specificity	This antibody recognizes Human PLCB1 (C-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	phospholipase C beta 1
Database Link	Entrez Gene 23236 Human UniProt ID Q9NQ66
Background	The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.
Synonyms	Phospholipase C-I, PLC beta1, PLC-I, Phospholipase C-beta-1, PLC-beta-1, KIAA0581
Note	Molecular Weight: 138567 Da
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Alzheimer's disease, Calcium signaling pathway, Chemokine signaling pathway, Gap junction, GnRH signaling pathway, Huntington's disease, Inositol phosphate metabolism, Long-term depression, Long-term potentiation, Melanogenesis, Metabolic pathways, Phosphatidylinositol signaling system, Vascular smooth muscle contraction, Wnt signaling pathway

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