VAM1 (MPP6) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, WB
Recommend Dilution	Flow cytometry:  1/10-1/50. Western blot:  1/500-1/100. Enzyme immunoassay:  1/1000.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated - corresponding to the central region (between 367-396aa) of human MPP6 / MAGUK p55 subfamily member 6
Specificity	This antibody recognizes MPP6 / MAGUK p55 subfamily member 6.
Formulation	PBS with 0.09% (W/V) Sodium azide State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	membrane palmitoylated protein 6
Database Link	Entrez Gene 56524 MouseEntrez Gene 51678 Human UniProt ID Q9NZW5
Background	MPP6 is a member of the p55-like MAGUK subfamily. Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies - DLG-like, ZO1-like , p55-like and LIN2-like - based on their size and the presence of additional domains [Tseng et al., 2001; PubMed 11311936].
Synonyms	VAM1
Note	Molecular Weight: 61117 Da
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency

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