delta 2 Catenin (CTNND2) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Peptide ELISA: 1/1000. Western Blot: 1/1000. Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 1131-1159 amino acids from the C-terminal region of Human CTNND2
Specificity	This antibody reacts to CTNND2.
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	132656 Da
Gene Name	catenin delta 2
Database Link	Entrez Gene 18163 MouseEntrez Gene 1501 Human UniProt ID Q9UQB3
Background	This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome.
Synonyms	CTNND2, NPRAP, Delta-catenin, Neurojungin, GT24
Reference Data
Protein Families	Druggable Genome

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