AMCase (CHIA) (N-term) Rabbit Polyclonal Antibody
CAT#: AP50895PU-N
AMCase (CHIA) (N-term) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | FC, WB |
Recommend Dilution | Peptide ELISA: 1/1000. Western blot: 1/100 - 1/500. Flow cytometric: 1/10 - /50. |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 20-47 amino acids from the N-terminal region of human CHIA. |
Specificity | This antibody reacts to CHIA. |
Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Predicted Protein Size | 52271 Da |
Gene Name | chitinase, acidic |
Database Link | |
Background | CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins. |
Synonyms | Acidic mammalian chitinase, CHIA, TSA1902 |
Reference Data | |
Protein Families | Secreted Protein |
Protein Pathways | Amino sugar and nucleotide sugar metabolism |
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