ATP6V1B1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP50307PU-N

ATP6V1B1 (C-term) rabbit polyclonal antibody, Aff - Purified



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CNY 6,160.00


货期*
5周

规格
    • 400 ul

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution ELISA: 1/1000.
Western blotting: 1/100 - 1/500.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 471-501 amino acids from the C-terminal region of human ATP6V1B1
Specificity This antibody reacts to ATP6V1B1.
Formulation PBS containing 0.09% (W/V) sodium azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity chromatography on Protein A
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name ATPase H+ transporting V1 subunit B1
Background This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq].
Synonyms V-ATPase subunit B 1, ATP6B1, VATB, VPP3
Note Molecular Weight: 56833 Da
Reference Data
Protein Families Druggable Genome
Protein Pathways Epithelial cell signaling in Helicobacter pylori infection, Metabolic pathways, Oxidative phosphorylation, Vibrio cholerae infection
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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