ARHGEF6 (C-term) Rabbit Polyclonal Antibody
CAT#: AP50239PU-N
ARHGEF6 (C-term) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | ELISA: 1/1,000. Western blotting: 1/1,000. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 614-641 amino acids from the C-terminal region of human ARHGEF6 |
Specificity | This antibody reacts to ARHGEF6. |
Formulation | PBS containing 0.09% (W/V) sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | Rac/Cdc42 guanine nucleotide exchange factor 6 |
Database Link | |
Background | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. |
Synonyms | COOL2, KIAA0006, PIXA, Alpha-Pix, COOL-2 |
Note | Molecular Weight: Isoform2 71kd. 87499 Da |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Pancreatic cancer, Regulation of actin cytoskeleton |
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