UBR4 (C-term) Goat Polyclonal Antibody

CAT#: AP33295PU-N

UBR4 (C-term) goat polyclonal antibody, Aff - Purified



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CNY 5,371.00


货期*
4周

规格
    • 100 ug

Product images

Specifications

Product Data
Applications ELISA, IHC
Recommend Dilution Peptide ELISA: 1/128000 (Detection Limit).
Immunohistochemistry on Paraffin Sections: 5-10 µg/ml. In paraffin embedded Spleen shows various types of subnuclear staining in select splenocytes and additional membrane plus cytoplasm staining elsewhere.
Reactivity Bovine, Canine, Human, Mouse, Rat
Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence from the C Terminus of the protein sequence according to NP_065816.2.
Specificity This antibody recognizes UBR4 / ZUBR1.
Formulation Tris saline, pH~7.3
State: Aff - Purified
State: Liquid purified Ig fraction
Stabilizer: 0.5% BSA
Preservative: 0.02% Sodium Azide
Concentration lot specific
Purification Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name ubiquitin protein ligase E3 component n-recognin 4
Background p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions.
Synonyms KIAA0462, KIAA1307, RBAF600, ZUBR1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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