stabilin1 (STAB1) (C-term) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	Peptide ELISA: 1/8000 (Detection Limit). Immunohistochemistry on Paraffin Sections: 3-5 µg/ml. In paraffin embedded Human Spleen shows endothelial staining.
Reactivity	Bovine, Canine, Human, Porcine
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-DFPDTQRILTVK, from the C Terminus of the protein sequence according to NP_055951.2.
Specificity	This antibody recognizes Stabilin-1 at C-term.
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purfied Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Antigen Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	stabilin 1
Database Link	Entrez Gene 23166 Human UniProt ID Q9NY15
Background	Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes (Entrez gene 23166). Cellular localization: Membrane; Single-pass type I membrane protein.
Synonyms	Stabilin-1, FEEL1, FEEL-1, CLEVER-1, KIAA0246
Reference Data

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