TAPA1 (CD81) Rat Monoclonal Antibody [Clone ID: QV-6A8-S3]

CAT#: AP32979PU-N

TAPA1 (CD81) rat monoclonal antibody, clone QV-6A8-S3, Purified



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CNY 5,660.00


货期*
5周

规格
    • 100 ug

Cited in 1 publication.

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Specifications

Product Data
Clone Name QV-6A8-S3
Applications ELISA, FC, WB
Recommend Dilution Flow Cytometry: 1.2 µg/106 cells.
ELISA: 1/200-1/400.
Cell based ELISA
with intakt, transiently transfected cells: 1/200-1/400.
Reactivity Human
Host Rat
Clonality Monoclonal
Immunogen cDNA encoding Human CD81
Specificity Recognizes Human CD81. 
Other species not tested.
Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.
Formulation PBS, pH 7.2
State: Purified
State: Liquid purified IgG fraction
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name CD81 molecule
Background CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL) (1). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins (2,3). CD81 is an essential HCV host factor as silencing of CD81 expression by CD81-specific monoclonal antibodies in hepatoma cells inhibits HCV entry (4).
Synonyms S5.7; TAPA-1; TAPA1; Tetraspanin-28; Tspan-28; TSPAN28
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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