USP15 (C-term) Goat Polyclonal Antibody

CAT#: AP31856PU-N

USP15 (C-term) goat polyclonal antibody, Aff - Purified



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CNY 5,371.00


货期*
4周

规格
    • 100 ug

Product images

Specifications

Product Data
Applications ELISA, IHC
Recommend Dilution Peptide ELISA: 1/2000 (Detection Limit).
Immunohistichemistry on Paraffin sections: 2.5-3.8 µg/ml.
In paraffin embedded Human Liver shows patterned intracellular staining in hepatocytes.
Reactivity Bovine, Canine, Human, Mouse, Porcine, Rat
Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence from the C Terminus of the protein sequence according to NP_006304.1.
Specificity Recognizes USP15 at C-term.
Formulation Tris buffered saline, pH~7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Immunoaffinity Chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name ubiquitin specific peptidase 15
Background Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
Synonyms Ubiquitin carboxyl-terminal hydrolase 15, KIAA0529, Unph-2, Unph4
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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