Frizzled 9 (FZD9) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	Peptide ELISA: Detection Limit: 1/32000. Western Blot: Preliminary experiments in Kidney lysates from Human, Mouse and Rat gave no specific signal but low background (at antibody concentration up to 1 µg/ml). Immunohistochemistry on Paraffin Sections: 5-10 µg/ml. In paraffin embedded Human Testis shows acrosomal staining of spermatids.
Reactivity	Human, Mouse, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence from the C Terminus of the protein sequence according to NP_003499.1.
Specificity	Recognizes CD349 / FZD9.
Formulation	Tris saline, pH~7.3 with 0.02% Sodium Azide and 0.5% BSA State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	frizzled class receptor 9
Database Link	Entrez Gene 8326 Human UniProt ID O00144
Background	Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The Frizzled 9 gene is located within the Williams syndrome common deletion region of chromosome 7. Frizzled 9 is critical for hippocampal development and is likely to be a contributing factor to the neurodevelopmental and behavioral phenotype of patients with Williams syndrome. Expressed predominantly in adult and fetal brain, testis, eye, skeletal muscle and kidney. Moderately expressed in pancreas, thyroid, adrenal cortex, small intestine and stomach. Detected in fetal liver and kidney.
Synonyms	Fz-9, hFz9
Reference Data

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